Scientific and Process Technology

Senior Director

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About the job

Are you looking for a career change? Do you want to work for a company that uses a novel approach to the development of vaccines and immunotherapies targeting infectious and other immune-mediated diseases?

Invenia Group has exclusively partnered with a growing start-up that is currently seeking a Senior Director of Purification, Development, and Scale-Up based in Massachusetts to join the team, where you will have a focus on Multiple Antigen Presenting System (MAPS), a highly efficient vaccine technology.

Role responsibilities: 

The successful person will be responsible for developing a robust 10-30 liter scale prototype recombinant protein purification process for lead candidates. You will manufacture proteins suitable for use in IND-enabling toxicology studies and be responsible for tech transfer to CMOs to manufacture proteins to support Clinical trial material. You will also be responsible for the following: 

  • Work with CMOs to scale up to commercial scale
  • Drive Process characterization studies (PCS) and Process Performance Qualifications (PPQs) to support BLA submission
  • Development of 10-30 litre scale prototype recombinant purification processes for lead candidates
  • Manufacture proteins suitable for IND studies
  • Execute process characterization and process performance qualifications to support BLA submission

What we are looking for: 

We are looking for someone with a Ph.D. in biochemistry / biochemical engineering or a related field, with 10-15 years of relevant industrial experience in bacterial expression and purification of recombinant proteins. You should have experience developing efficient purification for recombinant proteins and have expertise in immunological and biophysical protein characterization techniques.

Sound interesting? This is a fantastic opportunity to join a company that has raised significant funding in its last 3 funding rounds with over $360 million in total. To find out more information regarding this role, please apply.